Albert Wesker is best known as the architect of the T-Virus and the mastermind behind much of the Resident Evil series' central conflict. A former S.T.A.R.S. captain who founded the unit himself, Wesker operated a classic double life: publicly serving as an R.P.D. officer while secretly working as one of Umbrella Corporation's top researchers in biological warfare.
Intelligent, ruthless, and obsessed with power, Wesker saw humanity as heading toward inevitable collapse and positioned himself as the only one capable of reshaping civilization according to his vision. During the Raccoon City Outbreak, he pivoted his allegiances to a shadowy organization while simultaneously orchestrating Umbrella's downfall—not out of principle, but to seize control of the company's assets and rebuild it as his own empire. Later, he aligned with Tricell, Inc., continuing his mission to remake the world in his image.
Chris Redfield and Jill Valentine became his most persistent obstacles. As former S.T.A.R.S. agents dedicated to stopping him, they earned Wesker's deep hatred over the years, fueling an obsessive desire for revenge that only intensified with each confrontation.
Fans and official sources widely consider Wesker the primary antagonist of the entire franchise—a distinction that arguably surpasses even Ozwell E. Spencer's role in the series' mythology. He's remained central to the story from the original game through his major reappearance in CODE: Veronica and his position as the main villain of Resident Evil 5, while also pulling strings behind the scenes in numerous other entries. The film series similarly positioned him as its driving antagonistic force.
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